The Intima

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The intima : A new soil.

Weninger and colleagues, 1 in this issue of Circulation Research, have simply and elegantly reported on a piece of fundamental arterial biology totally unexplored before: the developmental origins of the intima in the siphon of the internal carotid artery. This site was chosen for study because the parasellar internal carotid artery in adults has the unwelcome fate of being highly prone to athe...

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Vessel Remodeling after Intima-to-Intima Contact Anastomosis

BACKGROUND Intima-to-intima microanastomotic vascular remodeling was explored, utilizing a polylactide-caprolactone absorbable vein coupler model (PAVCM), which was designed to simulate a non-absorbable counterpart system with the sole exception of being absorbable. METHODS Six New Zealand white rabbits were used. After transection of the jugular vein, 2 PAVCMs were placed, 1 at each transect...

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Neoplasia of Aortic Intima.

Two cases of arterial obstruction, in the region of the aortic bifurcation, are described. In both cases, cellular proliferation of neoplastic type was found to be causing the obstruction, and in one case small embolic metastases were found in the lower limbs and lungs. No primary tumour was found in any site other than the aortic intima itself. Two apparently similar cases have been reported i...

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Phospholipid synthesis in the human arterial intima.

The accumulation of lipids within the arterial intima represents an important feature in the development of the atherosclerotic lesion. Although much interest has been centered on the relationship between blood lipid levels and atherosclerosis, limited information is available in inan concerning the intimal metabolism of lipids and its possible role in lipid accumulation within the vessel wall....

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Sterol synthesis in the human arterial intima.

Intimal sterol synthesis was examined in isolated human arterial segments obtained at surgery or at postmortem examination. The tissues were incubated with acetate-1-(14)C and mevalonate-2-(14)C and the incorporation of these precursors into sterols was determined. Intimal sterols were isolated by multiple chromatographic techniques and purified by bromination and oxidation procedures. The resu...

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ژورنال

عنوان ژورنال: Circulation Research

سال: 1999

ISSN: 0009-7330,1524-4571

DOI: 10.1161/01.res.85.10.877